Hold , , , and to reset TWiLight Menu++ Settings.
Hold SELECT to directly go to the settings menu.
Hold to load the last ran ROM.
TWiLight Menu++ has 6 different themes you can pick from. These are alternative menus which all have different designs, some of them having completely separate navigational styles.
TWiLight Menu++, as the name implies, is just a menu. It doesn't actually load the ROMs itself. Here are the manual pages for the ROM loaders:
Want more information on TWiLight Menu++? Check out the Wiki: